Allostatic load

Allostatic Load and Preterm Birth

Preterm birth is a universal health problem that is one of the largest unmet medical needs contributing to the global burden of disease. Adding to its complexity is that there are no means to predict who is at risk when pregnancy begins or when women will actually deliver. Until these problems are addressed, there will be no interventions to reduce the risk because those who should be treated w...

Factor Structure Underlying Components of Allostatic Load

Allostatic load is a commonly used metric of health risk based on the hypothesis that recurrent exposure to environmental demands (e.g., stress) engenders a progressive dysregulation of multiple physiological systems. Prominent indicators of response to environmental challenges, such as stress-related hormones, sympatho-vagal balance, or inflammatory cytokines, comprise primary allostatic media...

Mitochondrial Nexus to Allostatic Load Biomarkers.

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Allostatic Load - a review of the literature

LETTER TO THE EDITOR Mitochondrial Nexus to Allostatic Load Biomarkers

A recent study by Wiley, Gruenewald, Karlamangla, and Seeman modeling multisystemic allostatic load (AL) was published inPsychosomatic Medicine (1). The observations reported in this article are consistent with the accumulating evidence published in this journal supporting the role of additive dysregulated biological and physiological processes in a wide range of diseases (2–5). We applaud this...